Bacterial Superantigens Promote Acute Nasopharyngeal Infection by Streptococcus pyogenes in a Human MHC Class II-Dependent Manner

Establishing the genetic determinants of niche adaptation by microbial pathogens to specific hosts is important for the management and control of infectious disease. Streptococcus pyogenes is a globally prominent human-specific bacterial pathogen that secretes superantigens (SAgs) as ‘trademark’ vir...

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Autori principali: Kasper, Katherine J., Zeppa, Joseph J., Wakabayashi, Adrienne T., Xu, Stacey X., Mazzuca, Delfina M., Welch, Ian, Baroja, Miren L., Kotb, Malak, Cairns, Ewa, Cleary, P. Patrick, Haeryfar, S. M. Mansour, McCormick, John K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038607/
https://ncbi.nlm.nih.gov/pubmed/24875883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004155
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