Mesenchymal gene program–expressing ovarian cancer spheroids exhibit enhanced mesothelial clearance

Metastatic dissemination of ovarian tumors involves the invasion of tumor cell clusters into the mesothelial cell lining of peritoneal cavity organs; however, the tumor-specific factors that allow ovarian cancer cells to spread are unclear. We used an in vitro assay that models the initial step of o...

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Detalhes bibliográficos
Main Authors: Davidowitz, Rachel A., Selfors, Laura M., Iwanicki, Marcin P., Elias, Kevin M., Karst, Alison, Piao, Huiying, Ince, Tan A., Drage, Michael G., Dering, Judy, Konecny, Gottfried E., Matulonis, Ursula, Mills, Gordon B., Slamon, Dennis J., Drapkin, Ronny, Brugge, Joan S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038562/
https://ncbi.nlm.nih.gov/pubmed/24762435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69815
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