Mesenchymal gene program–expressing ovarian cancer spheroids exhibit enhanced mesothelial clearance

Metastatic dissemination of ovarian tumors involves the invasion of tumor cell clusters into the mesothelial cell lining of peritoneal cavity organs; however, the tumor-specific factors that allow ovarian cancer cells to spread are unclear. We used an in vitro assay that models the initial step of o...

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Hlavní autoři: Davidowitz, Rachel A., Selfors, Laura M., Iwanicki, Marcin P., Elias, Kevin M., Karst, Alison, Piao, Huiying, Ince, Tan A., Drage, Michael G., Dering, Judy, Konecny, Gottfried E., Matulonis, Ursula, Mills, Gordon B., Slamon, Dennis J., Drapkin, Ronny, Brugge, Joan S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4038562/
https://ncbi.nlm.nih.gov/pubmed/24762435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI69815
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