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Clinical evaluation of BCL-2/X(L) levels pre- and post- HER2-targeted therapy
Our previous pre-clinical work defined BCL-2 induction as a critical component of the adaptive response to lapatinib-mediated inhibition of HER2. To determine whether a similar BCL-2 upregulation occurs in lapatinib-treated patients, we evaluated gene expression within tumor biopsies, collected befo...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8099090/ https://ncbi.nlm.nih.gov/pubmed/33951110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0251163 |
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