Multi-Parameter Exploration of HIV-1 Virus-Like Particles as Neutralizing Antibody Immunogens in Guinea Pigs, Rabbits and Macaques

Virus-like particles (VLPs) offer a platform to test the hypothesis that, since antibody binding to native envelope glycoprotein (Env) trimers results in HIV-1 neutralization, that native Env trimers presented in membranes may be useful for inducing neutralizing antibodies (nAbs) in a vaccine settin...

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Hlavní autoři: Tong, Tommy, Crooks, Ema T., Osawa, Keiko, Robinson, James E., Barnes, Mary, Apetrei, Cristian, Binley, James M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4037872/
https://ncbi.nlm.nih.gov/pubmed/24882891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2014.03.015
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