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An HSV-2 Trivalent Vaccine Is Immunogenic in Rhesus Macaques and Highly Efficacious in Guinea Pigs

A genital herpes vaccine is urgently needed to prevent pain and suffering, reduce the incidence of neonatal herpes, and decrease the risk of HIV acquisition and transmission that accompanies genital infection. We evaluated a trivalent HSV-2 subunit antigen vaccine administered with CpG and alum in r...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Awasthi, Sita, Hook, Lauren M., Shaw, Carolyn E., Pahar, Bapi, Stagray, Jacob A., Liu, David, Veazey, Ronald S., Friedman, Harvey M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5245903/
https://ncbi.nlm.nih.gov/pubmed/28103319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006141
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