An HSV-2 Trivalent Vaccine Is Immunogenic in Rhesus Macaques and Highly Efficacious in Guinea Pigs

A genital herpes vaccine is urgently needed to prevent pain and suffering, reduce the incidence of neonatal herpes, and decrease the risk of HIV acquisition and transmission that accompanies genital infection. We evaluated a trivalent HSV-2 subunit antigen vaccine administered with CpG and alum in r...

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Gepubliceerd in:PLoS Pathog
Hoofdauteurs: Awasthi, Sita, Hook, Lauren M., Shaw, Carolyn E., Pahar, Bapi, Stagray, Jacob A., Liu, David, Veazey, Ronald S., Friedman, Harvey M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2017
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5245903/
https://ncbi.nlm.nih.gov/pubmed/28103319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006141
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