An HSV-2 Trivalent Vaccine Is Immunogenic in Rhesus Macaques and Highly Efficacious in Guinea Pigs

A genital herpes vaccine is urgently needed to prevent pain and suffering, reduce the incidence of neonatal herpes, and decrease the risk of HIV acquisition and transmission that accompanies genital infection. We evaluated a trivalent HSV-2 subunit antigen vaccine administered with CpG and alum in r...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:PLoS Pathog
Asıl Yazarlar: Awasthi, Sita, Hook, Lauren M., Shaw, Carolyn E., Pahar, Bapi, Stagray, Jacob A., Liu, David, Veazey, Ronald S., Friedman, Harvey M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5245903/
https://ncbi.nlm.nih.gov/pubmed/28103319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006141
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