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Molecular basis for nanoscopic membrane curvature generation from quantum mechanical models and synthetic transporter sequences

We investigate the physical origin of peptide-induced membrane curvature by contrasting differences between H-bonding interactions of prototypical cationic amino acids, arginine (Arg) and lysine (Lys), with phosphate groups of phospholipid heads using quantum mechanical (QM) calculations of a minimu...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Schmidt, Nathan W., Lis, Michael, Zhao, Kun, Lai, Ghee Hwee, Alexandrova, Anastassia, Tew, Gregory N., Wong, Gerard C. L.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036524/
https://ncbi.nlm.nih.gov/pubmed/23061419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja308459j
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