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Molecular Stress-inducing Compounds Increase Osteoclast Formation in a Heat Shock Factor 1 Protein-dependent Manner

Many anticancer therapeutic agents cause bone loss, which increases the risk of fractures that severely reduce quality of life. Thus, in drug development, it is critical to identify and understand such effects. Anticancer therapeutic and HSP90 inhibitor 17-(allylamino)-17-demethoxygeldanamycin (17-A...

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Detalhes bibliográficos
Principais autores: Chai, Ryan C., Kouspou, Michelle M., Lang, Benjamin J., Nguyen, Chau H., van der Kraan, A. Gabrielle J., Vieusseux, Jessica L., Lim, Reece C., Gillespie, Matthew T., Benjamin, Ivor J., Quinn, Julian M. W., Price, John T.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036365/
https://ncbi.nlm.nih.gov/pubmed/24692538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.530626
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