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Mitochondrial Metabolism of Pyruvate Is Essential for Regulating Glucose-stimulated Insulin Secretion

It is well known that mitochondrial metabolism of pyruvate is critical for insulin secretion; however, we know little about how pyruvate is transported into mitochondria in β-cells. Part of the reason for this lack of knowledge is that the carrier gene was only discovered in 2012. In the current stu...

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Bibliografiske detaljer
Main Authors: Patterson, Jessica N., Cousteils, Katelyn, Lou, Jennifer W., Manning Fox, Jocelyn E., MacDonald, Patrick E., Joseph, Jamie W.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036342/
https://ncbi.nlm.nih.gov/pubmed/24675076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.521666
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