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Membrane-bound IL-12 and IL-23 serve as potent mucosal adjuvants when co-presented on whole inactivated influenza vaccines

BACKGROUND: Potent and safe adjuvants are needed to improve the efficacy of parenteral and mucosal vaccines. Cytokines, chemokines and growth factors have all proven to be effective immunomodulatory adjuvants when administered with a variety of antigens. We have previously evaluated the efficacy of...

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Autors principals: Khan, Tila, Heffron, Connie L, High, Kevin P, Roberts, Paul C
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036309/
https://ncbi.nlm.nih.gov/pubmed/24884849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-11-78
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