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Membrane-bound IL-12 and IL-23 serve as potent mucosal adjuvants when co-presented on whole inactivated influenza vaccines

BACKGROUND: Potent and safe adjuvants are needed to improve the efficacy of parenteral and mucosal vaccines. Cytokines, chemokines and growth factors have all proven to be effective immunomodulatory adjuvants when administered with a variety of antigens. We have previously evaluated the efficacy of...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Khan, Tila, Heffron, Connie L, High, Kevin P, Roberts, Paul C
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036309/
https://ncbi.nlm.nih.gov/pubmed/24884849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-11-78
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