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Membrane-bound IL-12 and IL-23 serve as potent mucosal adjuvants when co-presented on whole inactivated influenza vaccines

BACKGROUND: Potent and safe adjuvants are needed to improve the efficacy of parenteral and mucosal vaccines. Cytokines, chemokines and growth factors have all proven to be effective immunomodulatory adjuvants when administered with a variety of antigens. We have previously evaluated the efficacy of...

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Bibliografske podrobnosti
Main Authors: Khan, Tila, Heffron, Connie L, High, Kevin P, Roberts, Paul C
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036309/
https://ncbi.nlm.nih.gov/pubmed/24884849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-11-78
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