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Membrane-bound IL-12 and IL-23 serve as potent mucosal adjuvants when co-presented on whole inactivated influenza vaccines

BACKGROUND: Potent and safe adjuvants are needed to improve the efficacy of parenteral and mucosal vaccines. Cytokines, chemokines and growth factors have all proven to be effective immunomodulatory adjuvants when administered with a variety of antigens. We have previously evaluated the efficacy of...

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Detalhes bibliográficos
Main Authors: Khan, Tila, Heffron, Connie L, High, Kevin P, Roberts, Paul C
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036309/
https://ncbi.nlm.nih.gov/pubmed/24884849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1743-422X-11-78
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