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Salmonella flagellins are potent adjuvants for intranasally administered whole inactivated influenza vaccine
Bacterial flagellins are potent inducers of innate immune responses in the mouse lung because they bind to TLR5 expressed on the apical surfaces of airway epithelial cells. TLR engagement leads to the initiation of a signaling cascade that results in a pro-inflammatory response with subsequent up-re...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2009
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3187848/ https://ncbi.nlm.nih.gov/pubmed/19654062 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2009.07.058 |
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