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Inhibiting Tyrosine Phosphorylation of Protein Kinase Cδ (PKCδ) Protects the Salivary Gland from Radiation Damage

Radiation therapy for head and neck cancer can result in extensive damage to normal adjacent tissues such as the salivary gland and oral mucosa. We have shown previously that tyrosine phosphorylation at Tyr-64 and Tyr-155 activates PKCδ in response to apoptotic stimuli by facilitating its nuclear im...

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Autori principali: Wie, Sten M., Adwan, Tariq S., DeGregori, James, Anderson, Steven M., Reyland, Mary E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036201/
https://ncbi.nlm.nih.gov/pubmed/24569990
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.551366
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