Mitochondrial Dysfunction and Decrease in Body Weight of a Transgenic Knock-in Mouse Model for TDP-43

The majority of amyotrophic lateral sclerosis (ALS) cases as well as many patients suffering from frontotemporal lobar dementia (FTLD) with ubiquitinated inclusion bodies show TDP-43 pathology, the protein encoded by the TAR DNA-binding protein (Tardbp) gene. We used recombinase-mediated cassette ex...

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Κύριοι συγγραφείς: Stribl, Carola, Samara, Aladin, Trümbach, Dietrich, Peis, Regina, Neumann, Manuela, Fuchs, Helmut, Gailus-Durner, Valerie, Hrabě de Angelis, Martin, Rathkolb, Birgit, Wolf, Eckhard, Beckers, Johannes, Horsch, Marion, Neff, Frauke, Kremmer, Elisabeth, Koob, Sebastian, Reichert, Andreas S., Hans, Wolfgang, Rozman, Jan, Klingenspor, Martin, Aichler, Michaela, Walch, Axel Karl, Becker, Lore, Klopstock, Thomas, Glasl, Lisa, Hölter, Sabine M., Wurst, Wolfgang, Floss, Thomas
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2014
Θέματα:
Molecular Bases of Disease
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036193/
https://ncbi.nlm.nih.gov/pubmed/24515116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.515940
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