Molecular Basis for Preventing α-Synuclein Aggregation by a Molecular Tweezer

Recent work on α-synuclein has shown that aggregation is controlled kinetically by the rate of reconfiguration of the unstructured chain, such that the faster the reconfiguration, the slower the aggregation. In this work we investigate this relationship by examining α-synuclein in the presence of a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Acharya, Srabasti, Safaie, Brian M., Wongkongkathep, Piriya, Ivanova, Magdalena I., Attar, Aida, Klärner, Frank-Gerrit, Schrader, Thomas, Loo, Joseph A., Bitan, Gal, Lapidus, Lisa J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2014
Gaiak:
Molecular Bases of Disease
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036189/
https://ncbi.nlm.nih.gov/pubmed/24567327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.524520
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