A Novel “Molecular Tweezer” Inhibitor of α-Synuclein Neurotoxicity in Vitro and in Vivo

Aggregation of α-synuclein (α-syn) is implicated as being causative in the pathogenesis of Parkinson’s disease, multiple system atrophy, and dementia with Lewy bodies. Despite several therapies that improve symptoms in these disorders, none slow disease progression. Recently, a novel “molecular twee...

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Autori principali: Prabhudesai, Shubhangi, Sinha, Sharmistha, Attar, Aida, Kotagiri, Aswani, Fitzmaurice, Arthur G., Lakshmanan, Ravi, Ivanova, Magdalena I., Loo, Joseph A., Klärner, Frank-Gerrit, Schrader, Thomas, Stahl, Mark, Bitan, Gal, Bronstein, Jeff M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer-Verlag 2012
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3337029/
https://ncbi.nlm.nih.gov/pubmed/22373667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-012-0105-1
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