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Ovarian Cancer Cell Heparan Sulfate 6-O-Sulfotransferases Regulate an Angiogenic Program Induced by Heparin-binding Epidermal Growth Factor (EGF)-like Growth Factor/EGF Receptor Signaling

Heparan sulfate (HS) is a component of cell surface and extracellular matrix proteoglycans that regulates numerous signaling pathways by binding and activating multiple growth factors and chemokines. The amount and pattern of HS sulfation are key determinants for the assembly of the trimolecular, HS...

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Autors principals: Cole, Claire L., Rushton, Graham, Jayson, Gordon C., Avizienyte, Egle
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4036170/
https://ncbi.nlm.nih.gov/pubmed/24563483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.534263
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