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Structure of the Toll-Spätzle complex, a molecular hub in Drosophila development and innate immunity
Drosophila Toll receptors are involved in embryonic development and the immune response of adult flies. In both processes, the only known Toll receptor ligand is the human nerve growth factor-like cystine knot protein Spätzle. Here we present the crystal structure of a 1:1 (nonsignaling) complex of...
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| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4036000/ https://ncbi.nlm.nih.gov/pubmed/24733933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1320678111 |
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