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Molecular Mechanism That Induces Activation of Spätzle, the Ligand for the Drosophila Toll Receptor
The Drosophila Toll receptor is activated by an endogenous cytokine ligand Spätzle. Active ligand is generated in response to positional cues in embryonic dorso-ventral patterning and microbial pathogens in the insect immune response. Spätzle is secreted as a pro-protein and is processed into an act...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2885229/ https://ncbi.nlm.nih.gov/pubmed/20378549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.098186 |
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