Selective inhibition of the function of tyrosine-phosphorylated STAT3 with a phosphorylation site-specific intrabody

Signal transducer and activator of transcription 3 (STAT3) is a multifunctional protein that participates in signaling pathways initiated by various growth factors and cytokines. It exists in multiple forms including those phosphorylated on Tyr(705) (pYSTAT3) or Ser(727) (pSSTAT3) as well as the unp...

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Detalhes bibliográficos
Main Authors: Koo, Mi Young, Park, Jiyoung, Lim, Jung Mi, Joo, Sei Yoon, Shin, Seung-Pil, Shim, Hyun Bo, Chung, Junho, Kang, Dongmin, Woo, Hyun Ae, Rhee, Sue Goo
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035943/
https://ncbi.nlm.nih.gov/pubmed/24733900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316815111
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