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Circadian rhythm of hyperoxidized peroxiredoxin II is determined by hemoglobin autoxidation and the 20S proteasome in red blood cells
The catalytic cysteine of the typical 2-Cys Prx subfamily of peroxiredoxins is occasionally hyperoxidized to cysteine sulfinic acid during the peroxidase catalytic cycle. Sulfinic Prx (Prx–SO(2)H) is reduced back to the active form of the enzyme by sulfiredoxin. The abundance of Prx–SO(2)H was recen...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142998/ https://ncbi.nlm.nih.gov/pubmed/25092340 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401100111 |
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