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Peroxiredoxin Functions as a Peroxidase and a Regulator and Sensor of Local Peroxides
Peroxiredoxins (Prxs) contain an active site cysteine that is sensitive to oxidation by H(2)O(2). Mammalian cells express six Prx isoforms that are localized to various cellular compartments. The oxidized active site cysteine of Prx can be reduced by a cellular thiol, thus enabling Prx to function a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3281607/ https://ncbi.nlm.nih.gov/pubmed/22147704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R111.283432 |
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