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Impact of detubulation on force and kinetics of cardiac muscle contraction
Action potential–driven Ca(2+) currents from the transverse tubules (t-tubules) trigger synchronous Ca(2+) release from the sarcoplasmic reticulum of cardiomyocytes. Loss of t-tubules has been reported in cardiac diseases, including heart failure, but the effect of uncoupling t-tubules from the sarc...
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| 主要な著者: | , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2014
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4035744/ https://ncbi.nlm.nih.gov/pubmed/24863933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311125 |
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