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Impact of detubulation on force and kinetics of cardiac muscle contraction
Action potential–driven Ca(2+) currents from the transverse tubules (t-tubules) trigger synchronous Ca(2+) release from the sarcoplasmic reticulum of cardiomyocytes. Loss of t-tubules has been reported in cardiac diseases, including heart failure, but the effect of uncoupling t-tubules from the sarc...
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| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
The Rockefeller University Press
2014
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4035744/ https://ncbi.nlm.nih.gov/pubmed/24863933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201311125 |
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