CFTR and Anoctamin 1 (ANO1) contribute to cAMP amplified exocytosis and insulin secretion in human and murine pancreatic beta-cells

BACKGROUND: Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene lead to the disease cystic fibrosis (CF). Although patients with CF often have disturbances in glucose metabolism including impaired insulin release, no previous studies have tested the hypothesis that CFTR...

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Detaylı Bibliyografya
Asıl Yazarlar: Edlund, Anna, Esguerra, Jonathan LS, Wendt, Anna, Flodström-Tullberg, Malin, Eliasson, Lena
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4035698/
https://ncbi.nlm.nih.gov/pubmed/24885604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1741-7015-12-87
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