Potential Protection Against Type 2 Diabetes in Obesity Through Lower CD36 Expression and Improved Exocytosis in β-Cells

Obesity is a risk factor for type 2 diabetes (T2D); however, not all obese individuals develop the disease. In this study, we aimed to investigate the cause of differential insulin secretion capacity of pancreatic islets from donors with T2D and non-T2D (ND), especially obese donors (BMI ≥30 kg/m(2)...

詳細記述

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書誌詳細
出版年:Diabetes
主要な著者: Nagao, Mototsugu, Esguerra, Jonathan L.S., Asai, Akira, Ofori, Jones K., Edlund, Anna, Wendt, Anna, Sugihara, Hitoshi, Wollheim, Claes B., Oikawa, Shinichi, Eliasson, Lena
フォーマット: Artigo
言語:Inglês
出版事項: American Diabetes Association 2020
主題:
Islet Studies
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243297/
https://ncbi.nlm.nih.gov/pubmed/32198214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0944
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