Potential Protection Against Type 2 Diabetes in Obesity Through Lower CD36 Expression and Improved Exocytosis in β-Cells

Obesity is a risk factor for type 2 diabetes (T2D); however, not all obese individuals develop the disease. In this study, we aimed to investigate the cause of differential insulin secretion capacity of pancreatic islets from donors with T2D and non-T2D (ND), especially obese donors (BMI ≥30 kg/m(2)...

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Bibliographische Detailangaben
Veröffentlicht in:Diabetes
Hauptverfasser: Nagao, Mototsugu, Esguerra, Jonathan L.S., Asai, Akira, Ofori, Jones K., Edlund, Anna, Wendt, Anna, Sugihara, Hitoshi, Wollheim, Claes B., Oikawa, Shinichi, Eliasson, Lena
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Diabetes Association 2020
Schlagworte:
Islet Studies
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7243297/
https://ncbi.nlm.nih.gov/pubmed/32198214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db19-0944
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