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S-Adenosylhomocysteine inhibits NFκB-mediated gene expression in hepatocytes and confers sensitivity to TNF cytotoxicity
BACKGROUND: Chronic alcohol exposure results in liver injury that is driven in partby inflammatory cytokines such as tumor necrosis factor-α (TNF). Hepatocytes are normally resistant to the cytotoxic effects of TNF, but they become sensitized to TNF by chronic alcohol exposure. Recently we reported...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4035050/ https://ncbi.nlm.nih.gov/pubmed/24224954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acer.12315 |
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