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NF-κB UP REGULATION OF C/EBPβ MEDIATES HEPATOCYTE RESISTANCE TO TNF TOXICITY

The sensitization of hepatocytes to cell death from TNF underlies many forms of hepatic injury including that from toxins. Critical for hepatocyte resistance to TNF toxicity is activation of NF-κB signaling which prevents TNF-induced death by the up regulation of protective proteins. To further defi...

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Autors principals: Wang, Yongjun, Singh, Rajat, Xiang, Youqing, Greenbaum, Linda E., Czaja, Mark J.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2991433/
https://ncbi.nlm.nih.gov/pubmed/20979051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23929
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