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The PWWP domain of mammalian DNA methyltransferase Dnmt3b defines a new family of DNA-binding folds
The PWWP domain is a weakly conserved sequence motif found in >60 eukaryotic proteins, including the mammalian DNA methyltransferases Dnmt3a and Dnmt3b. These proteins often contain other chromatin-association domains. A 135-residue PWWP domain from mouse Dnmt3b (amino acids 223–357) has been str...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4035047/ https://ncbi.nlm.nih.gov/pubmed/11836534 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsb759 |
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