Elementary tetrahelical protein design for diverse oxidoreductase functions

Emulating functions of natural enzymes in man-made constructs has proven challenging. Here we describe a man-made protein platform that reproduces many of the diverse functions of natural oxidoreductases without importing the complex and obscure interactions common to natural proteins. Our design is...

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Bibliographic Details
Main Authors:	Farid, Tammer A, Kodali, Goutham, Solomon, Lee A, Lichtenstein, Bruce R, Sheehan, Molly M, Fry, Bryan A, Bialas, Chris, Ennist, Nathan M, Siedlecki, Jessica A, Zhao, Zhenyu, Stetz, Matthew A, Valentine, Kathleen G, Anderson, J L Ross, Wand, A Joshua, Discher, Bohdana M, Moser, Christopher C, Dutton, P Leslie
Format:	Artigo
Language:	Inglês
Published:	2013
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4034760/ https://ncbi.nlm.nih.gov/pubmed/24121554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.1362
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Elementary tetrahelical protein design for diverse oxidoreductase functions

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