Engineering oxidoreductases: maquette proteins designed from scratch

The study of natural enzymes is complicated by the fact that only the most recent evolutionary progression can be observed. In particular, natural oxidoreductases stand out as profoundly complex proteins in which the molecular roots of function, structure and biological integration are collectively...

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Detalhes bibliográficos
Main Authors: Lichtenstein, Bruce R., Farid, Tammer A., Kodali, Goutham, Solomon, Lee A., Anderson, J.L. Ross, Sheehan, Molly M., Ennist, Nathan M., Fry, Bryan A., Chobot, Sarah E., Bialas, Chris, Mancini, Joshua A., Armstrong, Craig T., Zhao, Zhenyu, Esipova, Tatiana V., Snell, David, Vinogradov, Sergei A., Discher, Bohdana M., Moser, Christopher C., Dutton, P. Leslie
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3525474/
https://ncbi.nlm.nih.gov/pubmed/22616867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20120067
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