Design of Amphiphilic Protein Maquettes: Controlling Assembly, Membrane Insertion, and Cofactor Interactions

We have designed polypeptides combining selected lipophilic (LP) and hydrophilic (HP) sequences that assemble into amphiphilic (AP) α-helical bundles to reproduce key structure characteristics and functional elements of natural membrane proteins. The principal AP maquette (AP1) developed here joins...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Discher, Bohdana M., Noy, Dror, Strzalka, Joseph, Ye, Shixin, Moser, Christopher C., Lear, James D., Blasie, J. Kent, Dutton, P. Leslie
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2005
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574520/
https://ncbi.nlm.nih.gov/pubmed/16156646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi050695m
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