Design of Amphiphilic Protein Maquettes: Controlling Assembly, Membrane Insertion, and Cofactor Interactions

We have designed polypeptides combining selected lipophilic (LP) and hydrophilic (HP) sequences that assemble into amphiphilic (AP) α-helical bundles to reproduce key structure characteristics and functional elements of natural membrane proteins. The principal AP maquette (AP1) developed here joins...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Discher, Bohdana M., Noy, Dror, Strzalka, Joseph, Ye, Shixin, Moser, Christopher C., Lear, James D., Blasie, J. Kent, Dutton, P. Leslie
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2005
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2574520/
https://ncbi.nlm.nih.gov/pubmed/16156646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi050695m
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg