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The fragile X syndrome d(CGG)n nucleotide repeats form a stable tetrahelical structure.

The fragile X mental retardation syndrome is associated with the expansion of trinucleotide 5'-d(CGG)-3' repeats within the FMR1 gene and with hypermethylation of the cytosine residues of these repeats. The expansion and hypermethylation may account for the suppression of the transcription...

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Bibliografiske detaljer
Main Authors: Fry, M, Loeb, L A
Format: Artigo
Sprog:Inglês
Udgivet: 1994
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC43907/
https://ncbi.nlm.nih.gov/pubmed/8197163
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