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PIP(2) regulation of KCNQ channels: biophysical and molecular mechanisms for lipid modulation of voltage-dependent gating
Voltage-gated potassium (Kv) channels contain voltage-sensing (VSD) and pore-gate (PGD) structural domains. During voltage-dependent gating, conformational changes in the two domains are coupled giving rise to voltage-dependent opening of the channel. In addition to membrane voltage, KCNQ (Kv7) chan...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2014
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4034418/ https://ncbi.nlm.nih.gov/pubmed/24904429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2014.00195 |
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