Basal NF-κB controls IL-7 responsiveness of quiescent naïve T cells

T cells are essential for immune defenses against pathogens, such that viability of naïve T cells before antigen encounter is critical to preserve a polyclonal repertoire and prevent immunodeficiencies. The viability of naïve T cells before antigen recognition is ensured by IL-7, which drives expres...

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Hlavní autoři: Miller, Michelle L., Mashayekhi, Mona, Chen, Luqiu, Zhou, Ping, Liu, Xindong, Michelotti, Monica, Tramontini Gunn, Nicole, Powers, Sarah, Zhu, Xiaoping, Evaristo, Cesar, Alegre, Maria-Luisa, Molinero, Luciana L.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034246/
https://ncbi.nlm.nih.gov/pubmed/24799710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315398111
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