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Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer

Generally, solid tumors (>400 mm(3)) are inherently acidic, with more aggressive growth producing greater acidity. If the acidity could be targeted as a biomarker, it would provide a means to gauge the pace of tumor growth and degree of invasiveness, as well as providing a basis for predicting re...

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Hlavní autoři: Viola-Villegas, Nerissa Therese, Carlin, Sean D., Ackerstaff, Ellen, Sevak, Kuntal K., Divilov, Vadim, Serganova, Inna, Kruchevsky, Natalia, Anderson, Michael, Blasberg, Ronald G., Andreev, Oleg A., Engelman, Donald M., Koutcher, Jason A., Reshetnyak, Yana K., Lewis, Jason S.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034234/
https://ncbi.nlm.nih.gov/pubmed/24785505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405240111
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