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pH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents

Here we review a novel class of delivery vehicles based on pH-sensitive, moderately polar membrane peptides, which we call pH (Low) Insertion Peptides (pHLIPs), that target cells located in the acidic environment found in many diseased tissues, including tumors. SpecificAcidity targeting by pHLIPs i...

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Pubblicato in:Mol Membr Biol
Autori principali: Andreev, Oleg A., Engelman, Donald M., Reshetnyak, Yana K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691209/
https://ncbi.nlm.nih.gov/pubmed/20939768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/09687688.2010.509285
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