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pH-sensitive membrane peptides (pHLIPs) as a novel class of delivery agents

Here we review a novel class of delivery vehicles based on pH-sensitive, moderately polar membrane peptides, which we call pH (Low) Insertion Peptides (pHLIPs), that target cells located in the acidic environment found in many diseased tissues, including tumors. SpecificAcidity targeting by pHLIPs i...

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Publicado en:Mol Membr Biol
Autores principales: Andreev, Oleg A., Engelman, Donald M., Reshetnyak, Yana K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691209/
https://ncbi.nlm.nih.gov/pubmed/20939768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/09687688.2010.509285
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