Understanding the pharmacological properties of a metabolic PET tracer in prostate cancer

Generally, solid tumors (>400 mm(3)) are inherently acidic, with more aggressive growth producing greater acidity. If the acidity could be targeted as a biomarker, it would provide a means to gauge the pace of tumor growth and degree of invasiveness, as well as providing a basis for predicting re...

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Bibliografiska uppgifter
Huvudupphovsmän: Viola-Villegas, Nerissa Therese, Carlin, Sean D., Ackerstaff, Ellen, Sevak, Kuntal K., Divilov, Vadim, Serganova, Inna, Kruchevsky, Natalia, Anderson, Michael, Blasberg, Ronald G., Andreev, Oleg A., Engelman, Donald M., Koutcher, Jason A., Reshetnyak, Yana K., Lewis, Jason S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2014
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034234/
https://ncbi.nlm.nih.gov/pubmed/24785505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1405240111
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