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Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death

A number of pathogens cause host cell death upon infection, and Yersinia pestis, infamous for its role in large pandemics such as the “Black Death” in medieval Europe, induces considerable cytotoxicity. The rapid killing of macrophages induced by Y. pestis, dependent upon type III secretion system e...

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Detalhes bibliográficos
Main Authors: Weng, Dan, Marty-Roix, Robyn, Ganesan, Sandhya, Proulx, Megan K., Vladimer, Gregory I., Kaiser, William J., Mocarski, Edward S., Pouliot, Kimberly, Chan, Francis Ka-Ming, Kelliher, Michelle A., Harris, Phillip A., Bertin, John, Gough, Peter J., Shayakhmetov, Dmitry M., Goguen, Jon D., Fitzgerald, Katherine A., Silverman, Neal, Lien, Egil
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034196/
https://ncbi.nlm.nih.gov/pubmed/24799678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403477111
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