Functional screen analysis reveals miR-26b and miR-128 as central regulators of pituitary somatomammotrophic tumor growth through activation the PTEN-AKT pathway

MicroRNAs have been involved in the pathogenesis of different types of cancer, however their function in pituitary tumorigenesis remains poorly understood. Cyclic-AMP (cAMP)-dependent protein kinase (PKA)-defective pituitaries occasionally form aggressive growth-hormone (GH)-producing pituitary tumo...

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Detalhes bibliográficos
Main Authors: Palumbo, Tiziana, Faucz, Fabio R., Azevedo, Monalisa, Xekouki, Paraskevi, Iliopoulos, Dimitrios, Stratakis, Constantine A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034118/
https://ncbi.nlm.nih.gov/pubmed/22614013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.190
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