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miR-26a and miR-214 down-regulate expression of the PTEN gene in chronic lymphocytic leukemia, but not PTEN mutation or promoter methylation

We previous found the expression level of PTEN was low in the chronic lymphocytic leukemia (CLL) patients. To assess the pathogenic contribution of the low expression of PTEN, we determined PTEN-regulating miRNA interference, PTEN promoter methylation and PTEN gene mutation condition in CLL. One hun...

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Dades bibliogràfiques
Publicat a:Oncotarget
Autors principals: Zou, Zhi-Jian, Fan, Lei, Wang, Li, Xu, Ji, Zhang, Run, Tian, Tian, Li, Jian-Yong, Xu, Wei
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359232/
https://ncbi.nlm.nih.gov/pubmed/25361012
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