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miR-26a and miR-214 down-regulate expression of the PTEN gene in chronic lymphocytic leukemia, but not PTEN mutation or promoter methylation

We previous found the expression level of PTEN was low in the chronic lymphocytic leukemia (CLL) patients. To assess the pathogenic contribution of the low expression of PTEN, we determined PTEN-regulating miRNA interference, PTEN promoter methylation and PTEN gene mutation condition in CLL. One hun...

詳細記述

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書誌詳細
出版年:Oncotarget
主要な著者: Zou, Zhi-Jian, Fan, Lei, Wang, Li, Xu, Ji, Zhang, Run, Tian, Tian, Li, Jian-Yong, Xu, Wei
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4359232/
https://ncbi.nlm.nih.gov/pubmed/25361012
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