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Functional screen analysis reveals miR-26b and miR-128 as central regulators of pituitary somatomammotrophic tumor growth through activation the PTEN-AKT pathway
MicroRNAs have been involved in the pathogenesis of different types of cancer, however their function in pituitary tumorigenesis remains poorly understood. Cyclic-AMP (cAMP)-dependent protein kinase (PKA)-defective pituitaries occasionally form aggressive growth-hormone (GH)-producing pituitary tumo...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4034118/ https://ncbi.nlm.nih.gov/pubmed/22614013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.190 |
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