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Allosteric Modulation of Muscarinic Acetylcholine Receptors

An allosteric modulator is a ligand that binds to an allosteric site on the receptor and changes receptor conformation to produce increase (positive cooperativity) or decrease (negative cooperativity) in the binding or action of an orthosteric agonist (e.g., acetylcholine). Since the identification...

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書目詳細資料
Main Authors: Jakubík, Jan, El-Fakahany, Esam E.
格式: Artigo
語言:Inglês
出版: MDPI 2010
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4034100/
https://ncbi.nlm.nih.gov/pubmed/27713379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph3092838
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