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Allosteric Modulation of Muscarinic Acetylcholine Receptors
An allosteric modulator is a ligand that binds to an allosteric site on the receptor and changes receptor conformation to produce increase (positive cooperativity) or decrease (negative cooperativity) in the binding or action of an orthosteric agonist (e.g., acetylcholine). Since the identification...
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| Autors principals: | , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4034100/ https://ncbi.nlm.nih.gov/pubmed/27713379 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph3092838 |
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