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Chimeric Restriction Enzymes: What Is Next?

Chimeric restriction enzymes are a novel class of engineered nucleases in which the non-specific DNA cleavage domain of FokI (a type IIS restriction endonuclease) is fused to other DNA-binding motifs. The latter include the three common eukaryotic DNA-binding motifs, namely the helix-turn-helix moti...

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Bibliographic Details
Main Authors: Chandrasegaran, Srinivasan, Smith, Jeff
Format: Artigo
Language:Inglês
Published: 1999
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033837/
https://ncbi.nlm.nih.gov/pubmed/10494832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1515/BC.1999.103
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