Cargando...
Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product
[Image: see text] AMSH, a conserved zinc metallo deubiquitinase, controls downregulation and degradation of cell-surface receptors mediated by the endosomal sorting complexes required for transport (ESCRT) machinery. It displays high specificity toward the Lys63-linked polyubiquitin chain, which is...
Gardado en:
| Main Authors: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American
Chemical Society
2014
|
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4033627/ https://ncbi.nlm.nih.gov/pubmed/24787148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi5003162 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|