Bone Regeneration using an Alpha 2 Beta 1 Integrin-Specific Hydrogel as a BMP-2 Delivery Vehicle

Non-healing bone defects present tremendous socioeconomic costs. Although successful in some clinical settings, bone morphogenetic protein (BMP) therapies require supraphysiological dose delivery for bone repair, raising treatment costs and risks of complications. We engineered a protease-degradable...

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Autori principali: Shekaran, Asha, García, José R., Clark, Amy Y., Kavanaugh, Taylor E., Lin, Angela S., Guldberg, Robert E., García, Andrés J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4033404/
https://ncbi.nlm.nih.gov/pubmed/24726536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.03.055
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