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Effects of protein dose and delivery system on BMP-mediated bone regeneration

Delivery of recombinant proteins is a proven therapeutic strategy to promote endogenous repair mechanisms and tissue regeneration. Bone morphogenetic protein-2 (rhBMP-2) has been used to promote spinal fusion and repair of challenging bone defects; however, the current clinically-used carrier, absor...

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Detalhes bibliográficos
Principais autores: Boerckel, Joel D., Kolambkar, Yash M., Dupont, Kenneth M., Uhrig, Brent A., Phelps, Edward A., Stevens, Hazel Y., García, Andrés J., Guldberg, Robert E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3129848/
https://ncbi.nlm.nih.gov/pubmed/21507479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.03.063
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